He wrote for the Back to the Future comic book series for Harvey Comics.
Dwayne McDuffie was a co-founder of Milestone Media which was geared towards comic books providing focus on minority characters. It's earliest titles which McDuffie wrote included Hardware, Icon, Blood Syndicate and Static.
He also went on to write the 2000 cartoon series based on Static which was retitled as Static Shock.
- Avengers Spotlight #26-29 (Marvel Comics 1989-1990)
- Damage Control Volume 2 #1-4 (Marvel Comics 1989)
- Double Dragon #1-4 (Marvel Comics 1991)
- Fantastic Four #542-553 (Marvel Comics 2007-2008)
- What If? Volume 2 #18 (Marvel Comics 1990)
- Justice League: Crisis on Two Earths (Writer)(2010)
- Josh Keaton provided the voice of both The Flash and Aquaman.
- All-Star Superman (Writer)(2011)
- Cathy Cavadini provided the voice of Catherine Grant.
- Justice League: Doom (Writer)(2012)